Arcane: League of Legends (2021) - S01E01 - Welcome to the Playground

Rebels from the repressed undercity of Zaun march across a bridge into Piltover, resulting in the brutal pushback by Piltover enforcers. During the ensuing violence, sisters Powder and Vi find their parents dead in the rubble and are taken in by Vander, the leader of the failed rebellion, as his own children. Years later, Vi and Powder rob a Piltovan penthouse with their adopted brothers, Mylo and Claggor. Powder steals a set of magical crystals and accidentally shatters one. This causes an explosion that destroys a large portion of the building. Returning to the undercity, the siblings encounter Deckard and his thugs; while they beat them in a fistfight, Powder is chased and loses the loot. Vander, now a barman and a community leader in Zaun, scolds the children for their carelessness, and attempts to smooth things over with Grayson, the Sheriff of the enforcers. Vi berates Mylo for calling Powder a "jinx" and reassures her sister that things will get better. In the lowest parts of the undercity, crime lord Silco extracts information from Deckard and tests a new mutagen known as Shimmer on a rat.